Cefixime is a third generation broad spectrum oral Cephalosporin. It acts by binding to PBP (Penicillin Binding Protein) receptor namely 1,1a, 1b, 3 and inhibits cell wall synthesis of bacteria. It is bactericidal in nature.
Clavulanic acid is irreversible beta-lactamase inhibitor. It covers chromosomally mediated and plasmid mediated beta lactamases with ESBLs. It is a beta-lactam drug that functions as a mechanism-based β-Lactamase inhibitor. When combined with cephalosporin group antibiotics, it can overcome antibiotic resistance in bacteria that secrete beta-lactamase, which otherwise inactivates most cephalosporins.