Atorvastatin reduces cholesterol synthesis in liver by Inhibiting HMGCoAReductase. Atorvastatin normalizes endothelial cell activity and facilitates reduction of lipid in plaque.

Fenofibrate is a Fibric Acid which also acts as Lipid Lowering Agent. Fibrates activate PPAR (Peroxisome Proliferator Activated receptors), especially PPAR-a that modulates carbohydrate, fat metabolism and adipose tissue differentiation