AMPHITERO (Liposomal Amphotericin B) is a lipid-associated formulation of the broad-spectrum polyene antifungal agent amphotericin B. It is active against clinically relevant yeasts and moulds, including Candida spp., Aspergillus spp. and filamentous moulds such as Zygomycetes and is approved for the treatment of invasive fungal infections. In vitro and in vivo studies have shown that liposomal amphotericin B remains closely associated with the liposomes in the circulation, thereby reducing the potential for nephrotoxicity and infusion-related toxicity associated with conventional amphotericin B.
AMPHITERO Injection is used for first line treatment for Mucormycosis. Systemic mycotic infections including Disseminated Candidiasis, Aspergillosis, Cryptococcosis, Histoplasmosis. It is also used for the treatment of Fever of Unknown Origin in neutropenic patients and Visceral Leishmaniasis.