Pregnancy:
Do not use during pregnancy, as Pazopanib may cause serious harm to the unborn baby. Women of childbearing potential should use effective contraception during treatment and for at least one month after the last dose. Men with partners of childbearing potential should also use effective contraception during treatment.
Breastfeeding:
Breastfeeding is not recommended during treatment and for the period advised by your doctor after stopping therapy.
Kidney Disorders:
Use with caution in patients with kidney disease. It is generally not recommended in severe kidney impairment unless specifically advised by a specialist.
Liver Disorders:
Patients with liver disease require careful monitoring, and dose adjustment may be necessary. Pazopanib is not recommended in moderate to severe liver impairment.
Blood Pressure:
This medicine commonly causes high blood pressure. Blood pressure should be monitored regularly throughout treatment.
Infection Risk:
Pazopanib may reduce blood cell counts, increasing the risk of infections. Inform your doctor immediately if you develop fever, chills, persistent cough, sore throat, or flu-like symptoms.
Bleeding & Wound Healing:
The medicine may impair wound healing and increase the risk of bleeding. Inform your doctor if you are scheduled for surgery or dental procedures.
Drug & Food Interactions:
Avoid grapefruit or grapefruit juice and consult your doctor before taking antacids, H2 blockers, proton pump inhibitors, or any other prescription or herbal medicines, as they may interfere with treatment.
Driving:
Avoid driving or operating machinery if you experience dizziness, fatigue, blurred vision, or drowsiness.
Common Side Effects:
High blood pressure, diarrhea, nausea, vomiting, decreased appetite, weight loss, fatigue, headache, taste changes, hair discoloration, skin pigmentation changes, and musculoskeletal pain. Seek immediate medical attention if you develop yellowing of the skin or eyes, severe abdominal pain, dark urine, chest pain, severe bleeding, or persistent diarrhea.
