Aceclofenac belongs to a group of anti-inflammatory drugs called NSAID's. It is non selective COX1/COX2 inhibitor. It decreases the synthesis of mediators of inflammation like Interleukin 1 beta (IL-1beta) & TNF (Tumor Necrosis Factor). Paracetamol is an antipyretic and analgesic drug. It exerts its analgesic action by inhibiting prostaglandin biosynthesis in the Central Nervous System (CNS) by blocking COX3. It is an antipyretic that can reduce fever by affecting hypothalamus that regulates the temperature of the body.Chlorzoxazone is a centrally-acting agent for painful musculoskeletal conditions It inhibits multisynaptic reflex which is responsible for producing and maintaining skeletal muscle spasm of varied etiology.