Caspofungin 50 mg and Caspofungin 70 mg Injections
CASPETERO (Caspofungin) as a fungicidal works by interfering with the production ?(1,3)-D-Glucan is an essential component of the cell wall. Inhibition of the synthesis of ?(1,3)-D-glucan produces a double effect, both fungistatic and fungicidal. The fungistatic effect results from blockade of the cell wall synthesis, reducing fungal growth. The fungicidal effect results from a change in the integrity of the cell wall, which loses its mechanical strength and becomes unable to resist the intracellular osmotic pressure, leading ultimately to destruction of the fungal cell Fungal cells exposed to Caspofungin have incomplete or defective cell walls, making them fragile and unable to grow.
CASPETERO (Caspofungin) is available as injectable therapy and should eb administered by slow intravenous infusion over approximately 1 hour CASPETERO (Caspofungin) is used for the treatment of fungal infections mainly caused by Aspergillus and Candida species, most commonly seen in hospitalized / ICU patients undergoing surgeries or organ implant. • Empirical therapy for presumed fungal infections in Febrile Neutropenic patients. • Treatment of Candidemia and Invasive Candidiasis • Treatment of Esophageal Candidiasis • Treatment of Invasive Aspergillosis in patients who are refractory to or intolerant of other therapies A single loading dose of 70 mg should be administered on day 1, followed by 50 mg daily thereafter